The inhibitory effect of TMK688, a novel anti‐allergic drug having both 5‐lipoxygenase inhibitory activity and anti‐histamine activity, against bronchoconstriction, leukotriene production and inflammatory cell infiltration in sensitized guinea pigs

Abstract

TMK688 appears to be a novel anti-allergic drug having inhibitory effects on both the bronchoconstriction and the infiltration of inflammatory cells during late asthmatic responses.