MicroRNA-101 Exerts Tumor-Suppressive Functions in Non-small Cell Lung Cancer through Directly Targeting Enhancer of Zeste Homolog 2

Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers

George A. Calin, Cinzia Sevignani, Calin Dan Dumitru et al. · Proceedings of the National Academy of Sciences · 2004 · 4.1K citations · Full text

Life Sciences, Genetics, Oncology +13

Role of Histone H3 Lysine 27 Methylation in Polycomb-Group Silencing

Ru Cao, Liangjun Wang, Hengbin Wang et al. · Science · 2002 · 3.8K citations

Life Sciences, Genetics, Molecular Biology +16

Unique microRNA molecular profiles in lung cancer diagnosis and prognosis

Nozomu Yanaihara, Natasha J. Caplen, Elise D. Bowman et al. · Cancer Cell · 2006 · 3K citations · Full text

Medicine, Molecular Biology, Oncology +14

The polycomb group protein EZH2 is involved in progression of prostate cancer

Sooryanarayana Varambally, Saravana M. Dhanasekaran, Ming Zhou et al. · Nature · 2002 · 2.7K citations · Full text

Life Sciences, Genetics, Molecular Biology +14

EZH2 is a marker of aggressive breast cancer and promotes neoplastic transformation of breast epithelial cells

Celina G. Kleer, Qi Cao, Sooryanarayana Varambally et al. · Proceedings of the National Academy of Sciences · 2003 · 1.6K citations · Full text

Medicine, Molecular Biology, Oncology +17