Publication | Open Access
Short communication: <i>Trypanosoma cruzi </i>lineage I in endomyocardial biopsy from a north‐eastern Brazilian patient at end‐stage chronic chagasic cardiomyopathy
34
Citations
11
References
2006
Year
BiologyNorth‐eastern Brazilian PatientTrypanosoma CruziCardiomyopathyParasitic ProtozoaAfrican TrypanosomiasisGeneticsEndomyocardial BiopsyPathologyShort CommunicationT Cruzi IiMedicineCardiologyParasitologyChagas Disease
Trypanosoma cruzi, the agent of Chagas disease, is genetically classified into two major evolutionary lineages, T. cruzi I and T. cruzi II. In Southern American Cone countries it is T cruzi II which causes most cases of severe chronic Chagas disease. Contrary to this, we isolated T. cruzi I nested in endomyocardial biopsies of a chronic chagasic patient with end-stage heart failure. Our finding should alert clinicians to the possibility of severe Chagas disease in all regions where T. cruzi circulates, regardless of its lineage.
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