Variants in the 10q26 Gene Cluster (<i>LOC387715</i>and<i>HTRA1</i>) Exhibit Enhanced Risk of Age-Related Macular Degeneration along with<i>CFH</i>in Indian Patients

Abstract

The present data provided an independent validation of the association of LOC387715 and HTRA1 SNPs, along with their risk estimates among Indian patients with AMD. These associations underscore their significant involvement in AMD susceptibility, which may be useful for predictive testing.