Systemic Transforming Growth Factor-??1 Gene Therapy Induces Foxp3+ Regulatory Cells, Restores Self-Tolerance, and Facilitates Regeneration Of Beta Cell Function in Overtly Diabetic Nonobese Diabetic Mice - Concepedia

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Systemic Transforming Growth Factor-??1 Gene Therapy Induces Foxp3+ Regulatory Cells, Restores Self-Tolerance, and Facilitates Regeneration Of Beta Cell Function in Overtly Diabetic Nonobese Diabetic Mice

82

Citations

25

References

2005

Year

Xunrong Luo, Hua Yang, Il Soo Kim, Fludd Saint-Hilaire, Dolca Thomas, Bishnu P. De, Engin Özkaynak, Thangamani Muthukumar, Wayne W. Hancock, Ronald G. Crystal,

Transplantation

Abstract

Our data demonstrate that systemic TGF-beta1 gene therapy blocks islet destructive autoimmunity, facilitates islet regeneration, and cures diabetes in diabetic NOD mice.

References

	Year	Citations

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