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A NEW SITE FOR ISLET TRANSPLANTATION—A PERITONEAL-OMENTAL POUCH
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1983
Year
Transplantation SurgeryIslet TransplantationHistory Of Islet TransplantationIntestinal TransplantationRat IsletsNew SiteInsulin ManagementDiabetesPhysiologyTissue TransplantationTransplant SurgerySurgeryOrgan PreservationPancreas TransplantationInsulin DeliveryMedicine
A new site for islet transplantation is described. A peritoneal-omental pouch was constructed in diabetic rats by encasing the omentum in a pouch formed from a strip of parietal peritoneum obtained from the recipient. Isografts of rat islets placed in the pouch maintained normoglycemia in the recipients and removal of the pouch resulted in a rapid return to a diabetic state. This site may be applicable to the transplantation of islets in human diabetes.