Mutations in <i>LZTR1</i> add to the complex heterogeneity of schwannomatosis

Abstract

Our data confirm the relationship between mutations in LZTR1 and schwannomatosis. They indicate that germline mutations in LZTR1 confer an increased risk of vestibular schwannoma, providing further overlap with NF2, and that further causative genes for schwannomatosis remain to be identified.