Hypertonic Saline and Pentoxifylline Attenuates Gut Injury After Hemorrhagic Shock: The Kinder, Gentler Resuscitation

Abstract

The attenuation in gut injury after postshock resuscitation with HSPTX is associated with downregulation of iNOS activity and subsequent proinflammatory mediator synthesis. HSPTX has the potential to be a superior resuscitation fluid with significant immunomodulatory properties.