Lack of lymphatic vascular specificity of vascular endothelial growth factor receptor 3 in 185 vascular tumors

Abstract

The results of the current study show that although VEGFR-3 shows specificity toward lymphatics in normal tissues, this receptor is distributed extensively in benign and malignant vascular tumors and therefore can be considered a novel marker in the assessment of endothelial cell differentiation of vascular neoplasms.