Human Corneal Epithelium-Derived Thymic Stromal Lymphopoietin Links the Innate and Adaptive Immune Responses via TLRs and Th2 Cytokines

Abstract

These findings provide the first evidence of TSLP induction in the human eye and suggest the novel phenomenon that human corneal epithelium-derived TSLP may serve as a link between the innate and adaptive immune responses. TSLP may become a novel therapeutic target for allergic and inflammatory ocular surface diseases.