A Mechanistic Role for Type III IFN-λ <sub>1</sub> in Asthma Exacerbations Mediated by Human Rhinoviruses - Concepedia

Concepedia

Publication | Open Access

A Mechanistic Role for Type III IFN-λ <sub>1</sub> in Asthma Exacerbations Mediated by Human Rhinoviruses

DOI Full Paper Access

98

Citations

42

References

2011

Year

E. Kathryn Miller, Johanna Zea Hernandez, Vera Wimmenauer, Bryan E. Shepherd, Diego R. Hijano, Romina Libster, María Elina Serra, Niranjan Bhat, Juan P. Batalle, Yassir A. Mohamed,

American Journal of Respiratory and Critical Care Medicine

Abstract

Our findings suggest that HRV infections in children with asthma are specifically associated with acute wheezing, and that type III IFN-λ(1) responses mediate exacerbations caused by HRV. Modulation of IFN- λ(1) should be studied as a therapeutic target for exacerbations caused by HRV.

References

	Year	Citations

Page 1