Hypertonic Saline and Pentoxifylline Reduces Hemorrhagic Shock Resuscitation-Induced Pulmonary Inflammation Through Attenuation of Neutrophil Degranulation and Proinflammatory Mediator Synthesis

Abstract

Collectively, the attenuation of pulmonary inflammation with HSPTX after shock when compared with RL is associated with downregulation of neutrophil activation, oxidative stress, and proinflammatory mediator production.