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Mitochondrial Uncoupling Protein 1 Expressed in the Heart of Transgenic Mice Protects Against Ischemic-Reperfusion Damage

DOIFull Paper Access

146

Citations

29

References

2004

Year

Jacqueline Hoerter, M. Mar González‐Barroso, Elodie Couplan, Philippe Matéo, C. Gelly, Anne‐Marie Cassard, Philippe Diolez, Frédéric Bouillaud
Circulation

Abstract

UCP1 activity is low under normoxia but is induced during ischemia-reperfusion. The presence of UCP1 mitigates reperfusion-induced damage, probably because it lowers mitochondrial hyperpolarization at reperfusion.

References

YearCitations

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