ANTIHISTAMINIC AND SPASMOLYTIC EFFECTS OF MUSK

Abstract

Musk (Kasturi), a dried prepucial secretion from male musk deer, has a wide range of activity in antagonizing the in vitro effects of-histamine, 5-hydroxy-tryptamine, bradykinin, prostaglandin, acetylcholine and the Schultz-Dale reaction on the guinea-pig ileum. Musk also diminished in rats, the increased capillary permeability induced by histamine and Russell’s viper venom.