Design and Synthesis of 2‘,3‘-Dideoxy- 2‘,3‘-didehydro-β-<scp>l</scp>-cytidine (β-<scp>l</scp>-d4C) and 2‘,3‘-Dideoxy-2‘,3‘-didehydro-β-<scp>l</scp>-5- fluorocytidine (β-<scp>l</scp>-Fd4C), Two Exceptionally Potent Inhibitors of Human Hepatitis B Virus (HBV) and Potent Inhibitors of Human Immunodeficiency Virus (HIV) in Vitro

Abstract

ADVERTISEMENT RETURN TO ISSUELetterNEXTDesign and Synthesis of 2',3'-Dideoxy- 2',3'-didehydro-β-l-cytidine (β-l-d4C) and 2',3'-Dideoxy-2',3'-didehydro-β-l-5- fluorocytidine (β-l-Fd4C), Two Exceptionally Potent Inhibitors of Human Hepatitis B Virus (HBV) and Potent Inhibitors of Human Immunodeficiency Virus (HIV) in VitroTai-Shun Lin, Mei-Zhen Luo, Mao-Chin Liu, Yong-Lian Zhu, Elizabeth Gullen, Ginger E. Dutschman, and Yung-Chi ChengView Author Information Department of Pharmacology and The Comprehensive Cancer Center, Yale University School of Medicine, New Haven, Connecticut 06520-8066 Cite this: J. Med. Chem. 1996, 39, 9, 1757–1759Publication Date (Web):April 26, 1996Publication History Received13 November 1995Published online26 April 1996Published inissue 1 January 1996https://pubs.acs.org/doi/10.1021/jm950836qhttps://doi.org/10.1021/jm950836qrapid-communicationACS PublicationsCopyright © 1996 American Chemical SocietyRequest reuse permissionsArticle Views745Altmetric-Citations106LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information SUBJECTS:Antimicrobial agents,Genetics,Pharmaceuticals,Toxicity,Viruses Get e-Alerts