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Antiplasmodial and antipyretic screening ofMangifera indica extract
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1998
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Stem Bark ExtractBioassay-guided IsolationAfrican TrypanosomiasisMedicineHerbal MedicineMalariaAntiparasitic AgentParasite GenomicsPhytopharmacologyToxicologyPlasmodium Yoelii NigeriensisMicrobiologyRepository ActivityPharmacologyParasitologyDrug Resistance
The stem bark extract of Mangifera indica was evaluated for antiplasmodial activity against Plasmodium yoelii nigeriensis. The extract was also screened for antipyretic activity in mice. The extract exhibited a schizontocidal effect during early infection, and also demonstrated repository activity. A reduction in yeast-induced hyperpyrexia was also produced by the extract. © 1998 John Wiley & Sons, Ltd.