Computed Tomography Correlates with Pulmonary Exacerbations in Children with Cystic Fibrosis

Abstract

This is the first study showing correlation between CT and a true clinical outcome. Change in CT scores correlates moderately well with the number of exacerbation. Poor correlation between change in FEV1 and exacerbations suggests that HRCT may be a more appropriate outcome surrogate for longitudinal studies of young children.