The Effects of Bupivacaine, L-Nitro-L-Arginine-Methyl Ester, and Phenylephrine on Cardiovascular Adaptations to Asphyxia in the Preterm Fetal Lamb

Abstract

In the preterm fetal lamb, clinically relevant plasma concentrations of bupivacaine achieved by intravenous infusion to the pregnant ewe (80% gestation) abolished some of the fetal cardiovascular adaptations to asphyxia induced by partial umbilical cord occlusion.