Liver and tumour tissue concentrations of TNF-alpha in cancer patients treated with TNF-alpha and melphalan by isolated liver perfusion

High-dose recombinant tumor necrosis factor alpha in combination with interferon gamma and melphalan in isolation perfusion of the limbs for melanoma and sarcoma.

D Liénard, Patricia Ewalenko, Jean-Baptiste Delmotte et al. · Journal of Clinical Oncology · 1992 · 723 citations

Pharmacy, Oncology, Pharmacotherapy +17

Phase I study of recombinant tumor necrosis factor in cancer patients.

Mark Blick, Stephen A. Sherwin, Michael G. Rosenblum et al. · PubMed · 1987 · 429 citations

Medicine, Oncology, Pharmacology +9

Biologic activities and mechanisms of action of tumor necrosis factor-alpha/cachectin.

Marja Jäättelä · PubMed · 1991 · 258 citations

Life Sciences, Immunology, Oncology +14

Estradiol enhances leukocyte binding to tumor necrosis factor (TNF)-stimulated endothelial cells via an increase in TNF-induced adhesion molecules E-selectin, intercellular adhesion molecule type 1, and vascular cell adhesion molecule type 1.

María C. Cid, Hynda K. Kleinman, D. S. Grant et al. · Journal of Clinical Investigation · 1994 · 237 citations · Full text

Life Sciences, Cell Biology, Immunology +16

A phase I trial of intravenously-administered recombinant tumor necrosis factor-alpha in cancer patients.

Bruce A. Feinberg, Razelle Kurzrock, Moshe Talpaz et al. · Journal of Clinical Oncology · 1988 · 223 citations

Medicine, Oncology, Pharmacology +16