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Isolation and identification of the C6-hydroxy and C20-hydroxy metabolites and glucuronide conjugate of methylprednisolone by preparative high-performance liquid chromatography from urine of patients receiving high-dose pulse therapy

Pharmaceutical ScienceGlucuronide ConjugatePharmacologyHigh-dose Pulse TherapyPharmacotherapyClinical ChemistryDrug DevelopmentChromatographyMedicineMetabolomicsPharmacokineticsC20-hydroxy MetabolitesDrug DiscoveryDrug Analysis