Contrast-Enhanced Ultrasound (CEUS) for Differentiating Between Hepatocellular and Cholangiocellular Carcinoma

Abstract

HCC and ICC differ to some extent in their CEUS enhancement pattern. Incomplete arterial hyperenhancement is more often seen in ICC than in HCC. A rim sign seems to be specific for ICC, but is only rarely present. However, in a case-to-case decision, due to overlapping characteristics, a reliable differentiation between the two tumor types by CEUS alone is very often not possible.