BILATERAL CHOROIDAL OSTEOMAS WITH POLYPOIDAL CHOROIDAL VASCULOPATHY

Abstract

In Brief Background: A choroidal osteoma is a benign osseous tumor typically arising in the juxtapapillary or peripapillary area. The major cause of visual loss is secondary to the development of a subretinal neovascular membrane. The pattern of neovascularization that develops with osteomas has been typically described as classic choroidal neovascularization (CNV). Methods: Interventional case report. Results: A case of bilateral polypoidal choroidal neovascularization (PCV) occurring with bilateral choroidal osteomas is described in a 55-year-old Japanese woman. To our knowledge, this variant form of vasogenesis has not previously been described in association with this tumor. Clinical, angiographic, and optical coherence tomographic features are discussed. Subretinal hemorrhage in the left eye from polypoidal neovascularization in the macula was successfully treated with photodynamic therapy. Conclusions: The association between choroidal osteoma and PCV may have a better prognosis than that with classic CNV. Indocyanine green angiography is a useful tool in characterizing the nature of the neovascularization. A case of bilateral choroidal osteomas with bilateral polypoidal choroidal neovascularization is presented, as demonstrated by fluorescein as well as indocyanine green angiography. Choroidal osteomas are typically associated with the development of classic choroidal neovascularization; to our knowledge, polypoidal choroidal neovascularization has not been previously reported.