American Journal of Clinical Oncology · 2004 · 34 citations · 27 references
This analysis of a randomized trial evaluating postoperative WBRT in the treatment of single metastases to the brain showed no difference in survival between RPA class I or II patients. In addition, the use of postoperative WBRT after complete surgical resection of single brain metastases results in substantially better control of disease in the brain independent of RPA classes I or II.
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A Randomized Trial of Surgery in the Treatment of Single Metastases to the Brain
Roy A. Patchell, Phillip A. Tibbs, John W. Walsh et al. · New England Journal of Medicine · 1990 · 3.1K citations · Full text