Journal of Liquid Chromatography · 1992 · 105 citations · 21 references
PharmacyChemical EngineeringAnalytical ChemistrySeparation ProcessesSeparation ScienceAnalytical ChromatographyChiral ChromatographyChiral SeparationChromatographic SeparationChromatographyElectrophoretic SeparationAnalytical ElectrophoresisCapillary ElectrophoresisCapillary Electrophoretic Chiral SeparationCapillary Zone ElectrophoresisChiral Capillary ElectrophoresisChiral Mobile PhasesEnantiomeric SeparationMobile Phase Effects
Abstract Capillary zone electrophoresis is shown to be useful for the separation of select enantiomers via the use of mobile phases containing cyclodextrins (CDs). Both native and chemically modified CDs are utilized herein. Parameters important in achieving enantiomeric separations are CD type, concentration, and mobile phase pH. In addition, rapid (1 minute) enantiomeric separations are demonstrated. Experimental parameters important in attaining short analysis times are discussed.
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