Biomedical applications of terahertz technology

E. Pickwell, Vincent P. Wallace

Journal of Physics D Applied Physics · 2006 · 899 citations · 55 references

Concepts

TL;DR

THz radiation predominantly excites vibrational modes in water, causing water absorption to dominate spectroscopy and imaging of soft tissues, yet THz methods offer advantages for pharmaceutical and clinical applications. We review the development of terahertz technology and describe a typical system used in biomedical applications. We consider applications ranging from THz spectroscopy of crystalline drugs to THz imaging of skin cancer.

Abstract

We review the development of terahertz (THz) technology and describe a typical system used in biomedical applications. By considering where the THz regime lies in the electromagnetic spectrum, we see that THz radiation predominantly excites vibrational modes that are present in water. Thus, water absorption dominates spectroscopy and imaging of soft tissues. However, there are advantages of THz methods that make it attractive for pharmaceutical and clinical applications. In this review, we consider applications ranging from THz spectroscopy of crystalline drugs to THz imaging of skin cancer.

References

55