The Journal of Cell Biology · 1976 · 81 citations · 10 references
Life SciencesBotanyMicrobiologyHeavy Metal ToxicologyHistopathologyPhycologyAlgal Cell BiologyAlgal CytologyAlgal MorphologyCellular UltrastructureCopper ToxicityGreen AlgaeAlgal UltrastructureCopper BiochemistryCopper BiogeochemistryCopper Toxicity In PlantsGreen Algal Cell StructureMicroanalysisUltrastructural AlterationsUltrastructural Characters
The results of ultrastructural studies and transmission electron microscope microanalysis of two Scenedesmus strains experimentally exposed to copper sulfate are presented. A fine-structural examination of the cells revealed the presence of nuclear inclusions in the form of central dense-core complexes. Cytoplasmic structures resembling the intranuclear inclusions were occasionally found in the cells. TEM-X-ray microanalysis of these structures has provided evidence that the inclusions contain copper. It is concluded that their presence may be regarded as a detoxifying mechanism.
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Robert A. Goyer, Bonnie C. Rhyne · PubMed · 1973 · 236 citations
Lead Poisoning: Rapid Formation of Intranuclear Inclusions
David D. Choie, G Richter · Science · 1972 · 103 citations
Pharmacy, Pathobiology, Toxicology +15