Concepedia

SA4503, a sigma-1 receptor agonist, prevents cultured cortical neurons from oxidative stress-induced cell death via suppression of MAPK pathway activation and glutamate receptor expression

Tuerxun Tuerhong, Tadahiro Numakawa, Naoki Adachi, Emi Kumamaru, Hiromi Kitazawa, Motoshige Kudo, Hiroshi Kunugi

Neuroscience Letters · 2009 · 54 citations · 22 references

DOI

Concepts

References

22

Sigma-1 Receptor Chaperones at the ER- Mitochondrion Interface Regulate Ca2+ Signaling and Cell Survival

Teruo Hayashi, Tsung‐Ping Su · Cell · 2007 · 1.7K citations · Full text

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The Jnk1 and Jnk2 Protein Kinases Are Required for Regional Specific Apoptosis during Early Brain Development

Chia‐Yi Kuan, Derek Yang, Deborah R. Samanta Roy et al. · Neuron · 1999 · 892 citations · Full text

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Persistent Activation of ERK Contributes to Glutamate-induced Oxidative Toxicity in a Neuronal Cell Line and Primary Cortical Neuron Cultures

Madalina Stanciu, Ying Wang, Ruth Kentor et al. · Journal of Biological Chemistry · 2000 · 539 citations · Full text

Neurotrophins are required for nerve growth during development

Kerry L. Tucker, Michaël Meyer, Yves‐Alain Barde · Nature Neuroscience · 2001 · 526 citations

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Characterization of two novel σ receptor ligands: antidystonic effects in rats suggest σ receptor antagonism

Rae R. Matsumoto, Wayne D. Bowen, Michael A. Tom et al. · European Journal of Pharmacology · 1995 · 266 citations

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