Concepedia

The effect of an inhibitor of matrix metalloproteinases on colonic inflammation in a trinitrobenzenesulphonic acid rat model of inflammatory bowel disease

Peter Sykes, Bhogal, Brampton, Chander, Whelan, Parsons, Bird

Alimentary Pharmacology & Therapeutics · 1999 · 73 citations · 8 references

DOI

Abstract

Dosing rats with TNBS-induced colitis using sulphasalazine or marimastat produced a significant reduction in tissue injury and inflammation.

References

8

Measurement of Cutaneous Inflammation: Estimation of Neutrophil Content with an Enzyme Marker

Peter P. Bradley, Dennis A. Priebat, Robert D. Christensen et al. · Journal of Investigative Dermatology · 1982 · 3.6K citations · Full text

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Hapten-Induced Model of Chronic Inflammation and Ulceration in the Rat Colon

Gerald P. Morris, Paul L. Beck, Margaret S. Herridge et al. · Gastroenterology · 1989 · 1.7K citations

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A novel coumarin‐labelled peptide for sensitive continuous assays of the matrix metalloproteinases

Christopher G. Knight, Frances Willenbrock, Gillian Murphy · FEBS Letters · 1992 · 705 citations

A major role for matrix metalloproteinases in T cell injury in the gut

Sylvia L. F. Pender, Simon Tickle, Andrew Docherty et al. · The Journal of Immunology · 1997 · 328 citations

The antiinflammatory moiety of sulfasalazine, 5-aminosalicylic acid, is a radical scavenger

I. Ahnfelt‐Rønne, Ole Haagen Nielsen · Inflammation Research · 1987 · 91 citations

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