Developmental Medicine & Child Neurology · 1997 · 149 citations · 16 references
MedicineChild HealthPediatricsChild DevelopmentPediatric DisabilityPediatric Rehabilitation MedicineCerebral PalsyMotor Development InterventionNeurodevelopmental DisordersNeurodevelopmental RehabilitationPediatric NeurorehabilitationPediatric Physical TherapyCerebral Palsy InterventionCerebral Palsy Motor DevelopmentNeurodevelopmental TherapyOccupational Therapy RemediationPediatric Neurological Rehabilitation
The purpose of this research was to evaluate the combined effect of intensive neurodevelopmental therapy (NDT) and casting in improving hand function, quality of upper-extremity movement and range of motion in children aged between 18 months and 4 years with cerebral palsy (CP). A randomized crossover design was used to evaluate the difference between intensive NDT plus casting and a less intensive regular occupational therapy (OT) program. Blinded assessments of hand function, quality of upper-extremity movement, and parents' perception of hand-function performance were carried out at baseline, 4 months (end of first intervention period), 6 months (after a 2-month 'washout' period), and 10 months (end of second intervention period). Analysis of the outcomes revealed no significant differences in hand function, quality of upper-extremity movement, or parents' perception of hand-function performance between the two treatment groups-intensive NDT plus casting or regular OT programs. There does not appear to be any beneficial effect of an increased amount of therapy for the children in this study.
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The Crossover Experiment for Clinical Trials
Byron Wm. Brown · Biometrics · 1980 · 375 citations
The Effects of Physical Therapy on Cerebral Palsy
Frederick B. Palmer, Bruce K. Shapiro, Renee C. Wachtel et al. · New England Journal of Medicine · 1988 · 276 citations