Osmium-Catalyzed Vicinal Oxyamination of Alkenes by <i>N</i>-(4-Toluenesulfonyloxy)carbamates

Abstract

N-(4-toluenesulfonyloxy)carbamates based on a range of common amine protecting groups serve as preformed nitrogen sources in the intermolecular osmium-catalyzed oxyamination reaction of a variety of mono-, di-, and trisubstituted alkenes. The reactions occur with low catalyst loadings and good yields and afford high regioselectivity for unsymmetrically substituted alkenes.