Antimicrobial Agents and Chemotherapy · 1991 · 35 citations · 15 references
Life SciencesMicrobiologyPharmacologyAntimicrobial PharmacologyAntimicrobial ResistanceMedical MicrobiologyAntibiotic ResistanceAntibiotic Resistance MechanismsBacterial InfectionsBeta-lactam ResistancePharmacokinetics Of AntimicrobialsResistance In Gram-negative BacteriaActive Transporter-mediated Drug EffluxAltered Drug UptakeChemotherapeutic EffluxDrug Uptake LimitationPharmacokinetics Of Antimicrobial AgentsQuinolone Resistance MechanismsResistance In Clinical IsolatesResistance Mechanisms In Staphylococci
The amount of sparfloxacin uptake was higher than that of norfloxacin uptake in Staphylococcus aureus. Moreover, energy-dependent reduction in quinolone uptake, probably due to active efflux of the quinolone, was observed. The reduction in quinolone uptake appeared to be associated with quinolone resistance in S. aureus.
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Stan Cohen, Laura M. McMurry, David C. Hooper et al. · Antimicrobial Agents and Chemotherapy · 1989 · 376 citations · Full text
Mechanisms of action of and resistance to ciprofloxacin.
David C. Hooper, J S Wolfson, E Y Ng et al. · PubMed · 1987 · 265 citations