Concepedia

Synthesis of novel 5-substituted indirubins as protein kinases inhibitors

Anne Beauchard, Yoan Ferandin, S. Frere, Olivier Lozach, Mélina Blairvacq, Laurent Meijer, Valérie Thiéry, Thierry Besson

Bioorganic & Medicinal Chemistry · 2006 · 98 citations · 10 references

DOI

Concepts

References

10

GSK-3-Selective Inhibitors Derived from Tyrian Purple Indirubins

Laurent Meijer, Alexios-Leandros Skaltsounis, Prokopios Magiatis et al. · Chemistry & Biology · 2003 · 815 citations · Full text

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Indirubins Inhibit Glycogen Synthase Kinase-3β and CDK5/P25, Two Protein Kinases Involved in Abnormal Tau Phosphorylation in Alzheimer's Disease

Sophie Leclerc, Matthieu Garnier, Ralph Hoessel et al. · Journal of Biological Chemistry · 2001 · 723 citations · Full text

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Inhibition of Cyclin‐Dependent Kinases by Purine Analogues

Walter Filgueira de Azevedo, Sophie Leclerc, Laurent Meijer et al. · European Journal of Biochemistry · 1997 · 720 citations · Full text

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Structural Basis for the Synthesis of Indirubins as Potent and Selective Inhibitors of Glycogen Synthase Kinase-3 and Cyclin-Dependent Kinases

Panagiotis Polychronopoulos, Prokopios Magiatis, Alexios‐Léandros Skaltsounis et al. · Journal of Medicinal Chemistry · 2004 · 376 citations · Full text

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Sequential Dephosphorylation of p34 on Thr-14 and Tyr-15 at the Prophase/Metaphase Transition

Annie Borgne, Laurent Meijer · Journal of Biological Chemistry · 1996 · 135 citations · Full text

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