American Journal of Alzheimer s Disease & Other Dementias® · 2011 · 274 citations · 31 references
MedicineGeriatric MedicineNeurologyDementiaFunctional DeclinePhysical ActivityAlzheimer DiseaseCognitive DeclineCognitive ImpairmentDementia RehabilitationFunctional Assessment In Older AdultsFunctional Impairment In Dementia6-Minute Walk TestCognitive Decline PreventionCognitive-functional RelationshipControl Group DesignFunctional Capacity DeclineFunctional Status MonitoringMental State ExaminationMobility Outcome Measurement
Motor inactivity is typical in the later stages of Alzheimer's disease although there is evidence that physical exercise can reduce depression and enhance performance of daily activities. The aim of this study was to determine whether a walking program could reduce the functional and cognitive decline of elderly nursing home residents in the later stages of Alzheimer's disease. A total of 21 patients (84 ± 5 years) were randomly assigned to a walking program (WG) or to a control group (CG). A 6-minute walking test (6WT), the Barthel index of activities of daily living (ADLs), and Mini-Mental State Examination (MMSE) tests were performed before and after 24 weeks of the program. The WG showed significant improvement in the 6WT (20%) and ADLs (23%), while the CG decreased in MMSE (-47%), the WG had a slower decline (-13%). This study indicates that it is possible to stabilize the progressive cognitive dysfunctions in nursing home residents with Alzheimer's disease through a specific walking program.
31
Marshal F. Folstein, Susan E. Folstein, Paul R. McHugh · Journal of Psychiatric Research · 1975 · 86.9K citations
Functional evaluation : Barthel index
F. I. Mahonery · Medical Entomology and Zoology · 1965 · 12.9K citations
Physical Activity and Public Health
William L. Haskell, I‐Min Lee, Russell R. Pate et al. · Circulation · 2007 · 6.5K citations · Full text
FUNCTIONAL EVALUATION: THE BARTHEL INDEX.
Florence Mahoney, DOROTHEA W. BARTHEL · PubMed · 1965 · 5.9K citations