Concepedia

Age-Stratified Pharmacokinetics of Ketorolac Tromethamine in Pediatric Surgical Patients

Richard M. Dsida, Melissa Wheeler, Patrick K. Birmingham, Zhao Wang, Corri L. Heffner, Charles J. Coté, Michael J. Avram

Anesthesia & Analgesia · 2002 · 52 citations · 18 references

DOI

Abstract

The literature suggests that ketorolac disposition differs between children and adults. We characterized ketorolac pharmacokinetics in 36 children. Body weight-normalized two-compartment pharmacokinetic variables did not differ among pediatric patients <17 yr old and were similar to adult values.

References

18

Comparison of Ketorolac and Morphine as Adjuvants

Mehernoor F. Watcha, M. Barry Jones, Richard G. Lagueruela et al. · Anesthesiology · 1992 · 171 citations · Full text

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Pharmacokinetics and Pharmacodynamics of d-Tubocurarine in Infants, Children, and Adults 

Dennis M. Fisher, Colette M. O'Keeffe, Donald R. Stanski et al. · Anesthesiology · 1982 · 139 citations · Full text

, , +13

Population pharmacodynamic model for ketorolac analgesia*

Jaap W. Mandema, Donald R. Stanski · Clinical Pharmacology & Therapeutics · 1996 · 138 citations

Pharmacokinetics of ketorolac tromethamine in humans after intravenous, intramuscular and oral administration

Donald Jung, Edward J. Mroszczak, L J Bynum · European Journal of Clinical Pharmacology · 1988 · 121 citations

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Neuromuscular Effects of Vecuronium (ORG NC45) in Infants and Children during N2O, Halothane Anesthesia

Dennis M. Fisher, Ronald D. Miller · Anesthesiology · 1983 · 93 citations · Full text

, , +14