Targeted Overexpression of EZH2 in the Mammary Gland Disrupts Ductal Morphogenesis and Causes Epithelial Hyperplasia

The polycomb group protein EZH2 is involved in progression of prostate cancer

Sooryanarayana Varambally, Saravana M. Dhanasekaran, Ming Zhou et al. · Nature · 2002 · 2.7K citations · Full text

Life Sciences, Genetics, Molecular Biology +14

EZH2 is a marker of aggressive breast cancer and promotes neoplastic transformation of breast epithelial cells

Celina G. Kleer, Qi Cao, Sooryanarayana Varambally et al. · Proceedings of the National Academy of Sciences · 2003 · 1.6K citations · Full text

Medicine, Molecular Biology, Oncology +17

Benign Breast Disease and the Risk of Breast Cancer

Lynn C. Hartmann, Thomas A. Sellers, Marlene H. Frost et al. · New England Journal of Medicine · 2005 · 942 citations · Full text

Medicine, Oncology, Pathology +17

Expression of the int-1 gene in transgenic mice is associated with mammary gland hyperplasia and adenocarcinomas in male and female mice

Ann Tsukamoto, Rudolf Grosschedl, Raphael C. Guzman et al. · Cell · 1988 · 748 citations

Veterinary Medicine, Genetics, Oncology +10

GATA-3 Maintains the Differentiation of the Luminal Cell Fate in the Mammary Gland

Hosein Kouros‐Mehr, Euan M. Slorach, Mark D. Sternlicht et al. · Cell · 2006 · 692 citations · Full text

Life Sciences, Cell Biology, Developmental Biology +15