Postoperative Cervical Myelopathy and Cord Compression Associated with the Use of Recombinant Bone Morphogenetic Protein-2 in Posterior Cervical Decompression, Instrumentation, and Arthrodesis

Abstract

Caution should be exercised with rh-BMP-2 use in posterior cervical applications when a laminectomy has been performed. The safe and effective dose and technique for application have yet to be determined. Seroma formation is possible, which can cause acute stenosis with cord compression and neurologic compromise.