Green Chemistry Letters and Reviews · 2010 · 28 citations · 32 references
Natural SciencesChemical EngineeringChemistryCatalysisGreen ChemistryOrganic ChemistryCatalyst DesignCatalytic MaterialsGreen CatalysisHeterogeneous CatalysisOrganic SynthesisZeolite CatalysisCatalyst RecyclingHeterogeneous Catalyst DesignMild Reaction ConditionsQuinoline SynthesisZeolite Catalyst DesignZeolite Catalyst SynthesisZeolite CatalystsZeolites
Abstract ZnO-beta zeolite, an inexpensive and mild catalyst, has been used for the synthesis of polyhydroquinolines in excellent yields from the one-pot four-component condensation of aldehydes, dimedone, ethyl acetoacetate, and ammonium acetate in ethanol at room temperature. The remarkable advantages offered by this method are a green catalyst, mild reaction conditions, simple work-up procedures, much faster reactions, and excellent yield of products. Furthermore, the catalyst could be reused several times keeping its initial activity in recycled reactions.
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