Concepedia

Synthesis, radiosynthesis and In vivo evaluation of 5-[3-(4-Benzylpiperidin-1-yl)prop-1-ynyl]-1,3-dihydrobenzoimidazol-2-[11C]one, as a potent NR1A/2B subtype selective NMDA PET radiotracer

Gaëlle Roger, Béatrice Lagnel, Laurent Besret, Yann Bramoullé, Christine Coulon, Michelle Ottaviani, Michael Kassiou, Michel Bottlaender, Héric Valette, Frédéric Dollé

Bioorganic & Medicinal Chemistry · 2003 · 30 citations · 28 references

DOI

Concepts

References

28

The anticonvulsant MK-801 is a potent N-methyl-D-aspartate antagonist.

Erik H.F. Wong, J A Kemp, Tony Priestley et al. · Proceedings of the National Academy of Sciences · 1986 · 1.8K citations · Full text

, , +15

Ketamine and phencyclidine cause a voltage-dependent block of responses to l-aspartic acid

Christopher R. Honey, Željka Miljković, John F. MacDonald · Neuroscience Letters · 1985 · 260 citations

, , +7

Regional, developmental and interspecies expression of the four NMDAR2 subunits, examined using monoclonal antibodies

David Laurie, Ilse Bartke, Ralf Schoepfer et al. · Molecular Brain Research · 1997 · 225 citations

, , +14

Multiple sites for the regulation of the N-methyl-D-aspartate receptor.

Ian J. Reynolds, R J Miller · Molecular Pharmacology · 1988 · 210 citations

, , +17

Binding of [3H]3-(2-carboxypiperazin-4-yl)propyl-1-phosphonic acid to rat brain membranes: a selective, high-affinity ligand for N-methyl-D-aspartate receptors.

Deborah E. Murphy, Jennifer Schneider, C. Boehm et al. · Journal of Pharmacology and Experimental Therapeutics · 1987 · 208 citations

, , +17