Controlled Submolecular Translational Motion in Synthesis: A Mechanically Interlocking Auxiliary

Abstract

Sew simple: How can you put a molecular bead on a thread when no recognition elements exist between them? A mechanically interlocking auxiliary assembles the macrocycle around a template, controlled submolecular translation moves the ring over the desired substrate and, finally, cleavage of the auxiliary leaves an apparently “impossible” rotaxane (see scheme). Supporting information for this article is available on the WWW under http://www.wiley-vch.de/contents/jc_2002/2004/z53606_s.pdf or from the author. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.