KIT gene exon 11 mutations in canine malignant melanoma

Gain-of-Function Mutations of c- <i>kit</i> in Human Gastrointestinal Stromal Tumors

Seiichi Hirota, Koji Isozaki, Y Moriyama et al. · Science · 1998 · 4.4K citations

KIT activation is a ubiquitous feature of gastrointestinal stromal tumors.

Brian P. Rubin, Samuel Singer, C. Tsao et al. · PubMed · 2001 · 968 citations

Gastroenterology, Pathology, Cancer Biology +16

Identification of mutations in the coding sequence of the proto-oncogene c-kit in a human mast cell leukemia cell line causing ligand-independent activation of c-kit product.

T Furitsu, Tohru Tsujimura, T. Tono et al. · Journal of Clinical Investigation · 1993 · 818 citations · Full text

Immunology, Signaling Pathway, Cell Regulation +16

KIT Extracellular and Kinase Domain Mutations in Gastrointestinal Stromal Tumors

Marcia L. Lux, Brian P. Rubin, Tara L. Biase et al. · American Journal Of Pathology · 2000 · 644 citations · Full text

Tumor Biology, Gastrointestinal Oncology, Medicine +8

<i>KIT</i> Gene Mutations and Copy Number in Melanoma Subtypes

Carol Beadling, Erick Jacobson‐Dunlop, F. Stephen Hodi et al. · Clinical Cancer Research · 2008 · 632 citations · Full text