Adalimumab effectively controlled recalcitrant generalized pustular psoriasis in an adolescent

Abstract

Generalized pustular psoriasis is a rare form of psoriasis which may be serious and can be fatal. We report here the treatment of an adolescent girl who responded to adalimumab after failing to respond to a combination of methotrexate, cyclosporin and isotretinoin, and having had a pustular reaction that followed the use of etanercept, but might have been triggered by an infection.