Journal of Neurochemistry · 1985 · 25 citations · 10 references
Life SciencesNeurosciencePhysiologyNeurobiophysicsNeurochemistryNeurophysiologyBlood-brain Barrier BiologyBlood-brain Barrier PenetrationCentral Nervous SystemCentral Nervous System PhysiologyCerebral Blood FlowVascular PermeabilityBlood-brain Barrier PermeabilityBlood-brain Barrier Transport StudiesBrain PermeabilityFluid Transport In TissueMicrovascular PermeabilityPassive Diffusion Across The Blood-brain BarrierTissue PermeabilityTransport In Brain Tissue
The kinetics of the movement of [14C]mannitol and [14C]inulin from the blood into the CNS of the rat were measured. The spinal cord was found to have a higher permeability to these two substances than the brain. It is likely that the channels through which the tracers diffused are larger in the capillaries of the spinal cord than those in the brain.
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