Plasma pregnenolone levels in cynomolgus monkeys following pharmacological challenges of the hypothalamic–pituitary–adrenal axis

Stress-induced elevations of gamma-aminobutyric acid type A receptor-active steroids in the rat brain.

R. H. Purdy, A. Leslie Morrow, Perry H. Moore et al. · Proceedings of the National Academy of Sciences · 1991 · 960 citations

Life Sciences, Neurobiology, Neuroscience +14

Psychiatric implications of basic and clinical studies with corticotropin-releasing factor

P W Gold, George P. Chrousos, Charles H. Kellner et al. · American Journal of Psychiatry · 1984 · 481 citations

Life Sciences, Neuroscience, Psychiatry +17

Memory-enhancing effects in male mice of pregnenolone and steroids metabolically derived from it.

James F. Flood, John E. Morley, E. Roberts · Proceedings of the National Academy of Sciences · 1992 · 437 citations

Life Sciences, Neuroscience, Pharmacology +17

Selective serotonin reuptake inhibitors directly alter activity of neurosteroidogenic enzymes

Lisa Griffin, Synthia H. Mellon · Proceedings of the National Academy of Sciences · 1999 · 388 citations

Medicine, Neuroscience, Pharmacology +17

Relationship between symptom severity and steroid variation in women with premenstrual syndrome: study on serum pregnenolone, pregnenolone sulfate, 5 alpha-pregnane-3,20-dione and 3 alpha-hydroxy-5 alpha-pregnan-20-one.

M Wang, L. Seippel, Robert H. Purdy et al. · The Journal of Clinical Endocrinology & Metabolism · 1996 · 339 citations

Medicine, Endocrinology, Gynecology +17