Syntheses of Optically Active α-Amino Acids from Esters of α-Keto Acids by Hydrogenolytic Asymmetric Transamination, A Solvent Effect

Abstract

Abstract Optically active α-amino acids were synthesized from esters of α-keto acid azomethines by catalytic hydrogenation. Solvent effect of the reaction was studied and the possible steric courses are discussed.