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Intestinal Glycoproteins of Germfree Rats. IV. Oligosaccharides Obtained by Chemical Degradation of a Water-soluble Glycoprotein Fraction.

DOIFull Paper Access

18

Citations

0

References

1975

Year

Jens K. Wold, Berit Smestad, Tore Midtvedt, Anna‐Britta Hörnfeldt, Rolf Servin, Hans Sternerup
Acta chemica Scandinavica/Acta chemica Scandinavica. B, Organic chemistry and biochemistry/Acta chemica Scandinavica. A, Physical and inorganic chemistry/Acta chemica Scandinavica. Series B. Organic chemistry and biochemistry/Acta chemica Scandinavica. Series A, Physical and inorganic chemistry

Abstract

Removal of sialic acid from the glycoprotein and subsequent degradation with sodium hydroxide-sodium borohydride resulted in the formation of a number of low-molecular weight carbohydrate compounds of which three were isolated and characterized: 2-deoxy-2-acetamido-D-galactitol; O-alpha-6-fucopyranosyl (1 leads to 2)-O-Beta-D-galactopyranosyl-(1 leads to 3)-2-deoxy-2-acetamido-D-galactitol (oligosaccharide I); O-Beta-D galactopyranosyl-(1 leads to 3)-2-deoxy-2-acetamido-D-galactitol (oligosaccharide II). From an acetolysate of the desialized glycoprotein a fourth component was obtained and characterized to be O-Beta-D-galactopyranosyl-(1 leads to 4)-2-deoxy-2-acetamido-D-glucose (oligosaccharide III).