Clinical experience with bethanidine in treatment of hypertension.

Abstract

At the present time probably most patients with high blood pressure in this country are being treated with guanethidine or methyldopa with or without the addition of an oral diuretic. Because of certain disadvantages of these two drugs in our experience (Lowther and Turner, 1963 ; Johnson et al., 1966) we have largely confined our attention during the past three years to debrisoquine (Kitchin and Turner, 1966) and bethan idine. Experience with the latter drug is the subject of this paper.