Concepedia

Ozonolysis of Acetals. (<i>1</i>) Ester Synthesis, (<i>2</i>) THP Ether Cleavage, (<i>3</i>) Selective Oxidation of β-Glycoside, (<i>4</i>) Oxidative Removal of Benzylidene and Ethylidene Protecting Groups

Pierre Deslongchamps, Claude Moreau

Canadian Journal of Chemistry · 1971 · 98 citations · 0 references

DOI

Concepts

Abstract

Ozone reacts very smoothly with acetals to give the corresponding esters. Tetrahydropyranyl ethers, β-glycopyranosides, ethylidene, or benzylidene derivatives are also oxidized whereas the α-glycopyranosides are inert.