Clinical efficacy of milbemycin oxime in the treatment of canine scabies: a study of 56 cases

Abstract

The purpose of this study was to determine the efficacy of orally administered milbemycin oxime in the treatment of canine scabies. The study includes 56 dogs with a clinical history and presentation compatible with canine sarcoptic mange. Scabies mites or eggs were found on microscopy of skin scrapings from all dogs in the study. The dogs were treated with milbemycin oxime at a dose of 2 mg kg −1 weekly for a total of three doses. All dogs were less pruritic or nonpruritic after the third treatment, but 29% of the dogs had increased pruritus and positive skin scrapings 3–6 weeks after the third treatment. The results of this study show less efficacy (71%) than previously reported.