Isoflurane—A Powerful Coronary Vasodilator in Patients with Coronary Artery Disease

Abstract

The coronary hemodynamic effects of 1% end-tidal isoflurane administered in oxygen-nitrogen by intermittent positive-pressure ventilation (IPPV) were investigated in 21 patients with stable coronary artery disease. Besides standard central hemodynamic measurements, coronary sinus blood flow was meas