Concepedia

Mechanisms of oncogenic KIT signal transduction in primary gastrointestinal stromal tumors (GISTs)

Anette Duensing, Fabíola Medeiros, Bryna McConarty, Nora Joseph, Dipak Panigrahy, Samuel Singer, Christopher D.�M. Fletcher, George D. Demetri, Jonathan A. Fletcher

Oncogene · 2004 · 345 citations · 41 references

DOI

Concepts

References

41

Gain-of-Function Mutations of c- <i>kit</i> in Human Gastrointestinal Stromal Tumors

Seiichi Hirota, Koji Isozaki, Y Moriyama et al. · Science · 1998 · 4.5K citations

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Efficacy and Safety of Imatinib Mesylate in Advanced Gastrointestinal Stromal Tumors

George D. Demetri, Margaret von Mehren, Charles D. Blanke et al. · New England Journal of Medicine · 2002 · 4.4K citations · Full text

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Kinase Mutations and Imatinib Response in Patients With Metastatic Gastrointestinal Stromal Tumor

Michael C. Heinrich, Christopher L. Corless, George D. Demetri et al. · Journal of Clinical Oncology · 2003 · 2.3K citations

, , +17

<i>PDGFRA</i> Activating Mutations in Gastrointestinal Stromal Tumors

Michael C. Heinrich, Christopher L. Corless, Anette Duensing et al. · Science · 2003 · 2.3K citations

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Effect of the Tyrosine Kinase Inhibitor STI571 in a Patient with a Metastatic Gastrointestinal Stromal Tumor

Heikki Joensuu, Peter Roberts‎, Maarit Sarlomo‐Rikala et al. · New England Journal of Medicine · 2001 · 2.1K citations · Full text

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